Efek Ekstrak Bawang Putih (Allium sativum L.) dalam Menekan Pertumbuhan Bakteri Salmonella typhi secara In vitro
DOI:
https://doi.org/10.33096/whj.v5i1.129Keywords:
Ekstrak bawang putih, Salmonella typhi, Pertumbuhan bakteriAbstract
Salmonella typhi is a Gram-negative bacterium that has no spores, moves with peritrichic flagellum, is facultative intracellular and facultative anaerobic. Garlic (Allium sativum) has been known for a long time to be used as a seasoning and medicine. The antibacterial activity of garlic can control pathogenic bacteria, both gram-negative and positive. To determine the effectiveness of Salmonella typhi bacteria growth given garlic extract (Allium sativum). This research is a true experiment post test using disc diffusion method. The higher the concentration of garlic extract (Allium sativum), the greater the inhibition zone obtained. The highest concentration of 100% garlic extract against Salmonella typhi bacteria has an inhibition zone of 14.4 mm with sensitive interpretation. Garlic extract (Allium sativum) has antibacterial effectiveness against the growth of Salmonella typhi bacteria
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2. Idrus HH, Yuniati L, Fadilah AM, Mangarengi Y, Sodiqah Y. Efektifitas Ekstrak Buah Sawo Manila (Achras Zapota L.) terhadap Salmonella Typhi dengan Metode Agar Difus. UMI Med J. 2019;3(1):1–11.
3. Afifah NR, Pawenang ET. Higea Jornal of Public Health. Higea J Public Heal Res Dev. 2019;3(2):263–73.
4. Idrus HH, Hatta M, Febriza A, Kasim VNA. Antibacterial activities of sapodilla fruit extract inhibiting Salmonella typhi on mice BALB/c. Int J Appl Pharm. 2019;11(Special Issue 5):121–6.
5. Imara F. Salmonella typhi Bakteri Penyebab Demam Tifoid. Pros Semin Nas Biol di Era Pandemi COVID-19 [Internet]. 2020;6(1):1–5. Available from: http://journal.uin-alauddin.ac.id/index.php/psb/
6. Indrayati S, Diana PE. Uji Efektifitas Larutan Bawang Putih (Allium sativum) terhadap pertumbuhan Bakteri Staphylococcus Epidermidis. J Kesehat PERINTIS (Perintis’s Heal Journal). 2020;7(1):22–31.
7. Purwanto Y ayu, Fadli Z, Hakim R. Interaksi antagonis kloramfenikol dengan fraksi n-heksana dan fraksi air umbi bawang putih ( Allium sativum l . ) terhadap Salmonella thypi. J Kedokt Komunitas [Internet]. 2022;10(2):1–9. Available from: http://jim.unisma.ac.id/index.php/jkkfk/article/view/15969%0Ahttp://jim.unisma.ac.id/index.php/jkkfk/article/viewFile/15969/12077
8. Rodriguez C, Ramlaoui D, Georgeos N, Gasca B, Leal C, Subils T, et al. Antimicrobial activity of the Lacticaseibacillus rhamnosus CRL 2244 and its impact on the phenotypic and transcriptional responses in carbapenem resistant Acinetobacter baumannii. Sci Rep [Internet]. 2023;13(1):1–13. Available from: https://doi.org/10.1038/s41598-023-41334-8
9. Mayasari U, Sapitri A. Uji Aktivitas Antibakteri Daun Sereh Wangi (Cymbopogon nardus) Terhadap Pertumbuhan Bakteri Streptococcus mutans. J Klorofil. 2019;3(2):15–9.
10. Pasaribu OY, Simaremare AP, Sibarani JP. Uji Aktivitas Antibakteri Dari Air Perasan Bawang Putih Terhadap Bakteri Salmonella Typhi. Nommensen J Med. 2020;6(1):9–12.
11. Dwei IP, Orde IM. Efektivitas Gel Ekstrak Etanol Bawang Putih ( Allium sativum L .) Terhadap Bakteri Staphylococcus aureus Effectiveness Of Garlic ( Allium sativum L .) Ethanol Extract On Bacteria Staphylococcus aureus. 2020;2(2).
12. Hasrianda EF, Setiarto RHB. Potensi Rekayasa Genetik Bawang Putih terhadap Kandungan Senyawa Komponen Bioaktif Allicin dan Kajian Sifat Fungsionalnya. J Pangan. 2022;31(2):167–90.
13. Purwantiningsih TI, Rusae A, Freitas Z. Uji In Vitro Antibakteri Ekstrak Bawang Putih sebagai Bahan Alami untuk Menghambat Bakteri Staphylococcus aureus dan Escherichia coli Garlic Extract Antibacterial In Vitro Test as Nature Inggredient to Inhibit Staphylococcus aureus and Escherichia coli. Sains Peternak. 2019;17(1):1–4.
14. Batiha GES, Beshbishy AM, Wasef LG, Elewa YHA, Al-Sagan AA, El-Hack MEA, et al. Chemical constituents and pharmacological activities of garlic (Allium sativum L.): A review. Nutrients. 2020;12(3):1–21.
15. Dwiyanti RD, Nurlailah N. Screening of Sengkuang (Dracontomelon dao (Blanco) Merr. & Rofe) as Antibacterial Escherichia coli. Med Lab Technol J. 2022;8(1):77–83.
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2024-06-30
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Efek Ekstrak Bawang Putih (Allium sativum L.) dalam Menekan Pertumbuhan Bakteri Salmonella typhi secara In vitro. (2024). Wal’afiat Hospital Journal, 5(1), 8-15. https://doi.org/10.33096/whj.v5i1.129
